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Updated: Jun 22, 2026
Control of Cell Geometry through Infrared Laser Assisted Micropatterning
Published on: July 10, 2021
Direct laser patterning of soft matter: photothermal processing of supported phospholipid multilayers with nanoscale
Mareike Mathieu1, Daniel Schunk, Steffen Franzka
1Fachbereich Chemie Physikalische Chemie and CeNIDE-Center for Nanointegration Duisburg-Essen, Universität Duisburg-Essen, Essen, Germany.
Abstract:
Direct laser patterning of supported phospholipid multilayers is investigated. Spin coating is used to fabricate stacked bilayers of 1,2-dioleoyl-sn-glycero-3-phosphate (DOPA). Photothermal processing with a focused laser beam at lambda = 514 nm allows removal of the coating at predefined positions without causing any significant change in adjacent areas. Moreover, processing with nanoscale precision is feasible despite the soft and fluid nature of phospholipid films. In particular, holes with diameters from 1.8 microm down to 300 nm and below are fabricated by using a 1/e(2) laser spot size of about 2.5 microm. In addition, patterning is also very flexible and can be carried out over macroscopic length scales and at short processing times. Considering these features photothermal laser processing constitutes a powerful tool for micro- and nanopatterning of phospholipid films.
