[Histological malignancy grade of renal cancer: karyo- and stereometric analysis]

Karyo- and stereometric analyses using a computer imaging scanner, an ocular grid, and a micrometer have established a significant association between the histological malignancy grade of non-metastatic clear-cell carcinoma of the kidney and the stage of the disease, TNM stage, tumor size, tumor portion comprising a clear-cell component, and various karyometric parameters. In addition, a correlation was found between the latter, TMN stage, and tumor size. A histological grading system of clear-cell carcinoma of the kidney has been developed, which involves the most complete and objective morphological characteristics of tumor cellular nuclei and nucleoli.