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Deep vein thrombosis associated with celiac disease
Esin Beyan1, Merve Pamukcuoglu, Cengiz Beyan
1Department of Internal Medicine, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Bratislavske Lekarske Listy
|June 11, 2009
Summary
Celiac disease, an autoimmune disorder, is rarely associated with venous thrombosis. This case highlights a patient who developed deep vein thrombosis in the leg during the acute phase of celiac disease.
Area of Science:
- Gastroenterology
- Hematology
Background:
- Celiac disease is an autoimmune disorder triggered by gluten ingestion.
- Venous thromboembolism is a known complication, but its association with celiac disease is infrequently reported.
Observation:
- A 44-year-old male presented with chronic diarrhea, diagnosed as celiac disease via endoscopy and serological tests.
- The patient subsequently developed acute deep venous thrombosis (DVT) in the left leg.
Findings:
- Diagnosis of celiac disease was confirmed by characteristic endoscopic and histopathological findings, along with positive IgA anti-gliadin and IgA anti-endomisium antibodies.
- Deep venous thrombosis was diagnosed via Doppler ultrasonography, with no other identifiable thrombotic risk factors.
Implications:
- This case underscores the importance of considering thromboembolic events in patients diagnosed with celiac disease, particularly during active disease phases.
- Effective management with a gluten-free diet and anticoagulation (warfarin) led to a favorable long-term outcome.
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