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Sleep in individuals with Cri du Chat syndrome: a comparative study
A P H M Maas1, R Didden, H Korzilius
1GROW School for Oncology and Developmental Biology, Maastricht University, 6200 MD Maastricht, the Netherlands. anneke.maas@gen.unimaas.nl
Journal of Intellectual Disability Research : JIDR
|June 11, 2009
Summary
Individuals with Cri du Chat syndrome (CDC) do not have more sleep problems than others with similar intellectual disabilities. Night waking issues were most frequent in CDC, suggesting further research is needed.
Area of Science:
- Neurodevelopmental disorders
- Sleep medicine
- Genetics
Background:
- Sleep problems are prevalent in individuals with intellectual disabilities.
- Limited research exists on sleep patterns in Cri du Chat syndrome (CDC).
Purpose of the Study:
- To investigate sleep problems and behaviors in children and adults with CDC.
- To compare sleep characteristics of individuals with CDC to those with non-specific intellectual disabilities (NS) and Down syndrome (DS).
Main Methods:
- A sleep questionnaire was administered to 30 individuals with CDC.
- Sleep data from CDC participants were compared with data from 30 individuals with NS and 30 individuals with DS.
Main Results:
- 30% of individuals with CDC reported sleep problems, compared to 23% with NS and 10% with DS.
- Night waking was the most common sleep issue in CDC.
- Behaviors associated with disordered breathing and poor sleep quality were frequent in CDC, occurring more often than in DS.
Conclusions:
- Individuals with CDC do not exhibit a higher likelihood of sleep problems compared to peers with similar demographic profiles.
- Night waking problems in CDC warrant further investigation.
- Future research should explore the underlying causes of sleep disturbances in CDC.
