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Updated: Jun 22, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Atrial fibrillation ablation: who comes into consideration?]
B-D Gonska1, H J Bauerle, T Japha
1Medizinische Klinik 3, St. Vincentius-Kliniken Karlsruhe, Akademisches Lehrkrankenhaus der Universität Freiburg, Südendstrasse 32, Karlsruhe, Germany. prof.gonska@vincentius-ka.de
Atrial fibrillation ablation, particularly pulmonary vein isolation, is a standard procedure. Early ablation in paroxysmal atrial fibrillation offers the best success rates for a curative outcome.
Area of Science:
- Electrophysiology
- Cardiology
Context:
- Atrial fibrillation (AF) ablation, guided by 2006/2007 guidelines, is now a standard electrophysiological procedure.
- Pulmonary vein isolation is a key technique for eliminating focal triggers of AF.
Purpose:
- To evaluate the efficacy of atrial fibrillation ablation based on the type of atrial fibrillation (paroxysmal vs. persistent/permanent).
- To determine the optimal timing for ablation procedures to maximize success rates and minimize the need for repeat interventions or ongoing drug therapy.
Summary:
- Early ablation in paroxysmal atrial fibrillation demonstrates the highest success rates.
- Persistent or permanent atrial fibrillation have lower success rates with ablation, often requiring repeat procedures and continued antiarrhythmic drug therapy.
- Current ablation techniques offer curative potential primarily for patients with paroxysmal atrial fibrillation.
Impact:
- Highlights the importance of early intervention for atrial fibrillation ablation success.
- Informs clinical decision-making regarding the use of ablation versus antiarrhythmic drugs for different forms of atrial fibrillation.
- Suggests limitations of current ablation techniques for advanced stages of atrial fibrillation, necessitating further research.
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