Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transcervical chorionic villus sampling and midtrimester oligohydramnios.

E Y Cheng1, D A Luthy, D E Hickok

  • 1Division of Perinatal Medicine, Swedish Hospital Medical Center, Seattle, WA 98104.

American Journal of Obstetrics and Gynecology
|October 1, 1991
PubMed
Summary

Transcervical chorionic villus sampling (CVS) may be associated with midtrimester oligohydramnios, a condition observed in 2.7% of CVS cases. Postprocedure bleeding and elevated alpha-fetoprotein were identified as risk factors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preliminary report: Surgical outcomes following genitoplasty in children with moderate to severe genital atypia.

Journal of pediatric urology·2018
Same author

Lipomyelomeningocele for the urologist: Should we view it the same as myelomeningocele?

Journal of pediatric urology·2017
Same author

Urinary tract infection after voiding cystourethrogram.

Journal of pediatric urology·2017
Same author

Prospective assessment of cosmesis before and after genital surgery.

Journal of pediatric urology·2016
Same author

Prenatal pharmacogenomics: a promising area for research.

The pharmacogenomics journal·2016
Same author

Editorial Introduction.

Journal of genetic counseling·2015

Area of Science:

  • Obstetrics and Gynecology
  • Fetal Medicine
  • Genetic Diagnosis

Background:

  • Midtrimester oligohydramnios is a significant complication in pregnancy.
  • Chorionic villus sampling (CVS) is a common first-trimester genetic diagnostic procedure.
  • The association between CVS and oligohydramnios requires further investigation.

Purpose of the Study:

  • To investigate the potential association between transcervical chorionic villus sampling (CVS) and the development of midtrimester oligohydramnios.
  • To compare the incidence of oligohydramnios in women undergoing CVS versus amniocentesis.
  • To identify risk factors for oligohydramnios following CVS.

Main Methods:

  • Prospective cohort study comparing women undergoing CVS with those undergoing amniocentesis.

Related Experiment Videos

  • Follow-up for incidence of midtrimester oligohydramnios (16-23 weeks' gestation).
  • Nested case-control analysis within the CVS group to assess risk factors.

    • Main Results:

    • Severe oligohydramnios developed in 12 (2.7%) of 442 women after CVS with normal fetal karyotypes.
    • No oligohydramnios was observed in 391 women who underwent amniocentesis (p = 0.01).
    • Postprocedure bleeding and elevated maternal serum alpha-fetoprotein were significantly associated with oligohydramnios after CVS (p < 0.01).

    Conclusions:

    • Transcervical CVS may be associated with an increased risk of midtrimester oligohydramnios.
    • Postprocedure bleeding and elevated maternal serum alpha-fetoprotein are risk factors for oligohydramnios post-CVS.
    • No perinatal survivors were noted in cases of midtrimester oligohydramnios.