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Updated: Jun 22, 2026

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
Published on: January 17, 2020
Application of the INAA technique for elemental analysis of metallic biomaterials used in dentistry
Em Cincu1, L Crăciun, Ioana Manea-Grigore
1Horia Hulubei National Institute for Research & Development in Physics and Nuclear Engineering (IFIN-HH), Bucharest-Magurele, 407 Atomistilor Street, P. O. Box MG-6, Bucharest 077125, Romania. cincue@nipne.ro, cincu.em@b.astral.ro
Abstract:
The sensitive nuclear analytical technique Instrumental Neutron Activation Analysis (INAA) has been applied on several types of metallic biomaterials (Heraenium CE, Ventura Nibon, Wiron 99 and Ducinox which are currently used for restoration in the dental clinics) to study its performance in elemental analysis and identify eventual limitations. The investigation has been performed by two NAA Laboratories and aimed at getting an answer to the question on how the biomaterials compositions influence the patients' health over the course of time, taking into account the EC Directive 94/27/EC recommendations concerning Ni toxicity.
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