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Related Experiment Video

Updated: Jun 22, 2026

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

Balloon-shaped cystic subaortic membrane.

Kamran Aghasadeghi¹, Amir Aslani, Ahmad Ali Amirghofran

¹Cardiology Department, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology

|June 12, 2009

Summary

A young man experienced shortness of breath due to a rare cystic subaortic membrane obstructing blood flow. Surgical excision successfully resolved the left ventricular outflow tract obstruction.

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Balloon-based Injury to Induce Myointimal Hyperplasia in the Mouse Abdominal Aorta

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Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

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Published on: April 15, 2021

Balloon-based Injury to Induce Myointimal Hyperplasia in the Mouse Abdominal Aorta

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Published on: February 7, 2018

Area of Science:

Cardiology
Cardiovascular Surgery
Medical Imaging

Background:

A 22-year-old male presented with a 4-month history of exertional dyspnea, indicating a potential cardiovascular issue.
Echocardiography is a crucial non-invasive imaging modality for evaluating cardiac structure and function.

Observation:

Transthoracic echocardiography identified a 2 x 2 cm balloon-shaped cystic mass on the left ventricular outflow tract (LVOT).
Continuous-wave Doppler revealed a significant mean LVOT gradient of 44 mmHg, suggesting obstruction.
Transesophageal echocardiography provided detailed visualization of the mass at the aorto-mitral continuity, confirming its origin.

Findings:

A cystic ballooning subaortic membrane was identified as the cause of the LVOT obstruction.
The pre-operative imaging findings correlated precisely with the intraoperative observations.
Successful surgical excision of the subaortic membrane was performed.

Implications:

This case highlights the importance of advanced echocardiography in diagnosing rare causes of left ventricular outflow tract obstruction.
Prompt surgical intervention can effectively relieve the obstruction and improve patient symptoms.
Understanding the morphology of such congenital anomalies is vital for surgical planning and successful outcomes.