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Reverse Genetics Mediated Recovery of Infectious Murine Norovirus
13:48

Reverse Genetics Mediated Recovery of Infectious Murine Norovirus

Published on: June 24, 2012

Role of cholesterol pathways in norovirus replication

Kyeong-Ok Chang1

  • 1Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, 1800 Denison Ave., Manhattan, KS 66506, USA. kchang@vet.ksu.edu

Journal of Virology
|June 12, 2009
PubMed
Summary

Norwalk virus replication is influenced by cholesterol pathways. Inhibiting cholesterol synthesis boosts viral RNA and protein, while blocking ACAT reduces it, highlighting cholesterol as a therapeutic target.

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