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Central fatigue after cycling evaluated using peripheral magnetic stimulation.

Ian J Kremenic1, Beth W Glace, S Simon Ben-Avi

  • 1Nicholas Institute of Sports Medicine and Athletic Trauma, Lenox Hill Hospital, New York, NY 10075, USA. ian@nismat.org

Medicine and Science in Sports and Exercise
|June 12, 2009
PubMed
Summary

Trained cyclists experience significant central fatigue during prolonged cycling. Peripheral magnetic stimulation (PMS) is an effective technique for identifying this central fatigue.

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Area of Science:

  • Exercise Physiology
  • Sports Science
  • Neuromuscular Function

Background:

  • Fatigue during exercise arises from both central and peripheral mechanisms.
  • Peripheral magnetic stimulation (PMS) offers a less discomforting method to assess these mechanisms compared to other techniques.
  • PMS can elicit substantial quadriceps contractions, exceeding 70% of maximal voluntary contraction (MVC).

Purpose of the Study:

  • To investigate the central versus peripheral contributors to fatigue in male cyclists during extended cycling.
  • To utilize a peripheral nerve magnetic stimulation (PNMS) approach for fatigue assessment.

Main Methods:

  • Eleven men (41 ± 3 years) underwent 2 hours of cycling at ~66% VO2peak with interspersed sprints and a time trial.
  • Quadriceps isometric strength was measured pre- and post-exercise using MVC, central activation ratio (CAR) via superimposed PMS, and PMS alone.

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  • Metabolic data and rating of perceived exertion (RPE) were monitored throughout the protocol.
  • Main Results:

    • Cycling led to a 22% decline in MVC and a 17% decrease in PMS-elicited force, indicating significant fatigue.
    • Central activation ratio (CAR) decreased from 83% to 71%, signifying a reduction in central motor drive.
    • Heart rate and RPE increased over the exercise duration, consistent with the physiological demands.

    Conclusions:

    • Prolonged cycling in trained individuals results in substantial central fatigue.
    • Peripheral magnetic stimulation (PMS) emerges as a potentially superior method for diagnosing central fatigue compared to the interpolated twitch technique.