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Updated: Jun 22, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sleep apnoea and sleep breathing disorders
1Regional Sleep Service, Aintree University Hospital, Liverpool L9 7AL.
Sleep apnoea, a sleep breathing disorder, causes significant disability. Excessive sleepiness links to respiratory failure, obesity, and hypertension, necessitating practical assessment and management strategies.
Area of Science:
- Sleep Medicine
- Respiratory Medicine
- Cardiology
Background:
- Sleep apnoea and related sleep breathing disorders are significant causes of medical, social, and occupational disability.
- Excessive daytime sleepiness is a common symptom with serious health implications.
Purpose of the Study:
- To review the practical assessment and management of sleep apnoea and related sleep breathing disorders.
- To highlight the association between excessive sleepiness and cardiometabolic syndrome components.
Main Methods:
- Literature review of current assessment techniques for sleep apnoea.
- Synthesis of management strategies for sleep-related breathing disorders.
- Discussion of the link between sleep apnoea, sleepiness, and metabolic health.
Main Results:
- Sleep apnoea contributes to widespread disability.
- Excessive sleepiness is linked to respiratory failure, obesity, hypertension, and insulin resistance.
- Effective assessment and management are crucial for patient outcomes.
Conclusions:
- Sleep apnoea and associated sleepiness require prompt and effective clinical attention.
- Management strategies should address both respiratory and metabolic aspects.
- Addressing sleep breathing disorders improves overall health and reduces disability.
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