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Updated: Jun 22, 2026
04:30
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
[Carotid stenting: an alternative to surgery?]
M Roffi1, V Pereira, Millan D San
1Service de cardiologie, HUG, 1211 Genève 14. marco.roffi@hcuge.ch
Revue Medicale Suisse
|June 13, 2009
Summary
Internal carotid artery stenosis causes ischemic strokes. Revascularization is recommended for symptomatic stenosis >50% and asymptomatic stenosis >=60% in select patients, with treatment often delayed until 70-80% narrowing in practice.
Area of Science:
- Vascular Surgery
- Neurology
- Cardiovascular Medicine
Context:
- Internal carotid artery stenosis is a significant cause of ischemic stroke, accounting for 10-20% of cases.
- Current guidelines recommend revascularization for symptomatic stenosis (>50%) and asymptomatic stenosis (>=60%) with low perioperative risk.
- Clinical practice often deviates, with treatment typically reserved for >70-80% asymptomatic stenosis.
Purpose:
- To review the indications for carotid revascularization in patients with internal carotid artery stenosis.
- To discuss the evidence supporting different thresholds for intervention in symptomatic and asymptomatic patients.
- To outline the factors influencing the choice between carotid endarterectomy and stenting.
Summary:
- Symptomatic stenosis >50% warrants revascularization.
- Asymptomatic stenosis >=60% is indicated for intervention if perioperative risk is <3%.
- Carotid artery stenting is a viable option, especially for high-risk surgical candidates.
Impact:
- Optimizing treatment strategies for carotid stenosis can reduce stroke incidence.
- Patient selection for revascularization should consider stenosis severity, symptoms, and individual risk factors.
- Understanding the nuances between guideline recommendations and clinical practice is crucial for effective patient management.
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