Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 22, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

The Characterization Tool: A knowledge-based stem cell, differentiated cell, and tissue database with a web-based

Inken Wohlers1, Harald Stachelscheid, Joeri Borstlap

  • 1Department of Experimental Surgery, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Germany; Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Germany.

Stem Cell Research
|June 13, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

National genomic projects in Asia and Africa: a review.

Human genomics·2026
Same author

Comparative Evaluation of hiPSC-Derived Brain Organoids as Platforms for Assessing Thyroid Hormone System Disrupting Chemicals.

Cells·2026
Same author

CRISPR/Cas9 engineered and whole-genome characterized KIT D816V-mutant human iPSC lines.

Stem cell research·2026
Same author

Time‑resolved multi-omic analysis of paclitaxel exposure in human iPSC‑derived sensory neurons unveils mechanisms of chemotherapy‑induced peripheral neuropathy.

Cell death & disease·2026
Same author

Lung tumouroids as a testing platform for precision CAR T cell therapy.

Nature biomedical engineering·2026
Same author

Generation of 5 hiPSC lines from pediatric patients with Heritable pulmonary arterial hypertension (HPAH) caused by heterozygous mutations in the TBX4 gene.

Stem cell research·2025
Same journal

Generation of an arrhythmogenic right ventricular cardiomyopathy-patient-derived iPS cell line with PKP2 and AKAP9 mutation (MUNIi022-A).

Stem cell research·2026
Same journal

Establishment and characterization of three human pluripotent stem cell lines from patients with spinocerebellar ataxia 27B (SCA27B).

Stem cell research·2026
Same journal

Characterization of induced pluripotent stem cell lines from patients of African American ancestry.

Stem cell research·2026
Same journal

Establishment of CRISPR/Cas9-edited LEMD2 knock-in (UKWCHFi001-B-1) and knock-out (UKWCHFi001-B-2) iPSC lines to investigate the mechanisms of LEMD2-associated cardiomyopathy.

Stem cell research·2026
Same journal

A human iPSC model with LATS1/2 knockdown (MUSIi012-A-9) for investigating Hippo signaling in stem cell.

Stem cell research·2026
Same journal

Establishment and characterization of two human pluripotent stem cell lines from patients with ATX-FGF14/spinocerebellar ataxia 27A (SCA27A).

Stem cell research·2026
See all related articles

The Characterization Tool is a novel database for stem cell research, offering a unified knowledge base on cell and tissue characteristics. It aids in establishing cell characterization standards using data mining and analysis of marker profiles.

Area of Science:

  • Stem cell biology
  • Bioinformatics
  • Cellular characterization

Background:

  • Growing stem cell research necessitates universal databases for cell and tissue characterization data.
  • Existing resources lack a common knowledge base for diverse characterization data types.

Purpose of the Study:

  • To introduce the Characterization Tool, a novel web-based knowledge database.
  • To facilitate the storage, processing, and analysis of diverse cell and tissue characterization data.

Main Methods:

  • Development of an ontology-based framework for data integration.
  • Implementation of secure user management for data input and modification.
  • Integration of data mining tools for marker profile analysis.

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Related Experiment Videos

Last Updated: Jun 22, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Main Results:

  • The Characterization Tool stores diverse characterization data (morphological, molecular, functional) across species.
  • It integrates in vivo and in vitro data, including marker expressions, cross-references, and images.
  • Currently holds over 7000 marker expressions for various human stem and differentiated cells.

Conclusions:

  • The Characterization Tool provides a valuable resource for stem cell research.
  • It supports the establishment of essential standards for cell characterization.
  • Facilitates stem cell isolation, propagation, and differentiation processes.