Related Experiment Video
Updated: Jun 22, 2026

Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research
Published on: August 31, 2013
[STARI--a new tick borne spirochetosis]
Joanna Zajkowska1, Anna M Moniuszko, Piotr Czupryna
1Klinika Chorób Zakaźnych i Neuroinfekcji Uniwersytetu Medycznego w Białymstoku. zajkowsk@neostrada.pl
Southern Tick Associated Rash Illness (STARI), caused by Borrelia lonestari bacteria and spread by the Amblyomma americanum tick, presents early symptoms similar to Lyme disease. Effective diagnosis and treatment decisions for STARI currently rely on clinical observation due to limitations in traditional methods.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Context:
- Southern Tick Associated Rash Illness (STARI), or Masters disease, is caused by Borrelia lonestari spirochetes.
- Transmission occurs via the Amblyomma americanum tick, commonly known as the Lone Star tick.
- STARI shares early clinical manifestations with Lyme borreliosis, including an Erythema migrans-like rash.
Purpose:
- To highlight the etiological agent and vector of STARI.
- To underscore the diagnostic challenges associated with STARI.
- To emphasize the current clinical basis for STARI treatment decisions.
Summary:
- Borrelia lonestari spirochetes are identified as the causative agents of STARI.
- The Amblyomma americanum tick serves as the primary vector for STARI transmission.
- Diagnostic limitations necessitate clinical judgment for initiating antibiotic therapy, mirroring Lyme borreliosis management.
Impact:
- Increased awareness of STARI as a distinct tick-borne illness.
- Highlights the need for improved diagnostic tools for STARI.
- Informs clinical practice regarding the management of STARI patients.
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