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Updated: Jun 22, 2026

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension
Published on: May 17, 2024
[Pharmacological hypertension therapy]
Ole Lederballe Pedersen1, Kent Lodberg Christensen, Lia E Bang
1Medicinsk Afdeling, Regionshospitalet Viborg, DK-8800 Viborg. lederballe@dadlnet.dk
Abstract:
Drug therapy in uncomplicated hypertension can be initiated with either ACE-inhibitors, angiotensin II receptor antagonists, calcium channel blockers or thiazides. In younger patients, the first three classes are preferable. Beta-blockers are first-line drugs for hypertension in patients with cardiac comorbidity. Initial combination therapy is indicated in high-risk patients where blood pressure reduction of > 20/10 mmHg is desired. Resistant hypertension generally calls for an increment in diuretic dosage and/or addition of a potassium-sparing diuretic.
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