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Updated: Jun 22, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Retinal vein occlusion and obstructive sleep apnea syndrome]
G Leroux les Jardins1, A Glacet-Bernard, S Lasry
1Service d'Ophtalmologie, Université Paris XII, Hôpital Intercommunal Créteil et hôpital Henri-Mondor (Assistance Publique des Hôpitaux de Paris), France.
Obstructive sleep apnea syndrome (OSAS) may be a new risk factor for retinal vein occlusion (RVO). This condition affects retinal microcirculation, potentially causing or worsening RVO, even in patients without other vascular issues.
Area of Science:
- Ophthalmology
- Sleep Medicine
- Cardiovascular Medicine
Background:
- Obstructive sleep apnea syndrome (OSAS) is a prevalent condition linked to various systemic diseases.
- OSAS is increasingly associated with cardiovascular, neurological, and ophthalmological conditions.
- Ophthalmological manifestations of OSAS include glaucoma, optic neuropathy, and visual field defects.
Observation:
- This study presents observations on three patients with retinal vein occlusion (RVO).
- These patients were diagnosed with OSAS.
- Notably, these patients lacked conventional vascular risk factors.
Findings:
- OSAS may contribute to the development or exacerbation of RVO.
- Mechanisms include nocturnal hypoxemia, hypercapnia, sleep fragmentation, and increased sympathetic activation.
- These factors can impair retinal microcirculation and increase arterial blood pressure.
Implications:
- OSAS represents a potential novel risk factor for RVO.
- Early detection and management of OSAS may be crucial for preventing RVO progression.
- Further research is warranted to confirm the association between OSAS and RVO.
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