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Related Concept Videos

Development of the Heart01:27

Development of the Heart

The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
Overview of the Heart01:07

Overview of the Heart

The heart, a muscular organ located in the chest, functions as the body's pump, circulating blood through the vascular system. It has four chambers: two atria on top and two ventricles below. The right atrium receives deoxygenated blood from the body and passes it to the right ventricle, which pumps it to the lungs for oxygenation. The left atrium receives oxygenated blood from the lungs and transfers it to the left ventricle, which pumps it to the rest of the body.
The heart's structure...
Pulse rhythm01:30

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Location and Orientation of the Heart01:13

Location and Orientation of the Heart

The human heart, despite its modest size and weight, is an organ of remarkable strength and endurance. Roughly the size of a fist, the heart weighs between 250 and 350 grams and is nestled within the mediastinum, the medial cavity of the thorax. It extends obliquely for about 12 to 14 cm, resting on the superior surface of the diaphragm. The heart is positioned anterior to the vertebral column and posterior to the sternum, with two-thirds of its mass lying to the left of the midsternal line.
Anatomy of the Heart01:27

Anatomy of the Heart

The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
Anatomy of the Heart01:20

Anatomy of the Heart

The heart is a hollow, muscular organ approximately the size of a fist, consisting of four chambers. It is enclosed in the pericardium, a fibrous sac with two layers: the visceral and parietal pericardium, separated by a fluid-filled space containing serous fluid to reduce friction.
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...

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Related Experiment Video

Updated: Jun 22, 2026

Semi-automated Optical Heartbeat Analysis of Small Hearts
12:10

Semi-automated Optical Heartbeat Analysis of Small Hearts

Published on: September 16, 2009

Project HeartBeat! Concept, development, and design.

Darwin R Labarthe1, Shifan Dai, R Sue Day

  • 1Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341-3717, USA. dlabarthe@cdc.gov

American Journal of Preventive Medicine
|June 16, 2009
PubMed
Summary
This summary is machine-generated.

Cardiovascular disease risk factors develop early in life. Project HeartBeat! tracked children

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Last Updated: Jun 22, 2026

Semi-automated Optical Heartbeat Analysis of Small Hearts
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Visualizing the Beating Heart in Drosophila
10:15

Visualizing the Beating Heart in Drosophila

Published on: September 28, 2009

Area of Science:

  • Pediatric cardiology and public health research.

Background:

  • Cardiovascular disease (CVD) risk factors emerge during childhood and adolescence.
  • Early identification and intervention are crucial for long-term cardiovascular health.

Purpose of the Study:

  • To investigate the developmental trajectories of major cardiovascular disease risk factors in children and adolescents.
  • To examine the relationships between growth, body composition, sexual maturation, and CVD risk factors.

Main Methods:

  • A mixed-longitudinal study design tracking 678 children and adolescents aged 8-18 years over 4 years.
  • Collected data included physical measurements, cardiac structure/function, blood lipids, blood pressure, diet, physical activity, and sexual maturation.
  • Utilized multilevel modeling to analyze approximately 5500 observations per variable for a synthetic cohort from ages 8 to 18.

Main Results:

  • Established age-specific trajectories for key CVD risk factors including cholesterol, triglycerides, blood pressure, and left ventricular mass.
  • Demonstrated associations between body composition, sexual maturation, and the development of these risk factors.
  • Adjusted for energy intake and physical activity to refine understanding of influencing factors.

Conclusions:

  • Childhood and adolescence represent critical periods for the dynamic development of cardiovascular disease risk factors.
  • Findings offer insights into the complex interplay of growth, maturation, and lifestyle on early CVD risk.
  • Suggests a novel approach to understanding and potentially mitigating cardiovascular risk during developmental years.