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Updated: Jun 22, 2026

Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice
Published on: January 16, 2015
Comparison of methods for measurement of smoking behavior: mouthpiece-based computerized devices versus direct
Melissa D Blank1, Steven Disharoon, Thomas Eissenberg
1Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA.
Introduction:
Understanding factors that influence tobacco use often involves detailed assessment of smoking behavior (i.e., puff topography) via mouthpiece-based, computerized devices. Research suggests that the use of a mouthpiece to evaluate topography may alter natural smoking behavior. This study was designed to compare topography measurement using mouthpiece-based methods (i.e., desktop and portable computerized devices) to methods that do not use a mouthpiece (i.e., direct observation).
Methods:
A total of 30 smokers (> or =15 full-flavor or light cigarettes/day) participated in six Latin square-ordered, 2.5-hr experimental sessions that were preceded by at least 8 hr of objectively verified tobacco abstinence (carbon monoxide level < or = 10 ppm). Each session consisted of participants smoking four cigarettes (own brand or Merit ultra-light) ad libitum, conventionally or using a desktop or portable device. Sessions were videotaped using a digital camcorder.
Results:
All three measurement methods were sensitive to oft-reported brand- and bout-induced changes. Topography measurement differed little between methods (across methods, all r values > .68), and each method was reliable (across bouts within each condition, most r values > .78). In contrast, participants perceived the use of either mouthpiece-based device to alter aspects of their smoking behavior (e.g., increased smoking difficulty, reduced enjoyment, altered cigarette taste; p < .05), relative to video recording only.
Discussion:
Although direct observational methods may be optimal for measuring certain smoking characteristics, logistical challenges posed by this method likely limit its usefulness. Together, these results suggest that mouthpiece-based devices offer a convenient and useful tool for researchers examining smoking topography.

