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Updated: Jun 22, 2026
06:59
Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Coronary stenting in warfarin treated patients
1Department of Cardiology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel. dzahger@bgu.ac.il
Summary
For patients needing both coronary stents and anticoagulation, avoid drug-eluting stents when possible. A short course of triple therapy followed by aspirin and warfarin is recommended to manage dual antiplatelet therapy and anticoagulation needs.
Area of Science:
- Cardiology
- Pharmacology
Background:
- Dual antiplatelet therapy (DAPT) is standard after coronary stent implantation.
- A subset of patients requires chronic anticoagulation, often for atrial fibrillation.
- No prospective trials guide therapy selection for this complex patient group.
Purpose of the Study:
- To review existing data on managing patients requiring both DAPT and anticoagulation.
- To provide practice recommendations for this clinical scenario.
Main Methods:
- Review of available data and literature.
- Synthesis of evidence to formulate clinical recommendations.
Main Results:
- Drug-eluting stents should be used cautiously in patients needing both DAPT and anticoagulation, particularly if not at high bleeding risk.
- A recommended regimen involves one month of triple therapy (aspirin, clopidogrel, warfarin).
Conclusions:
- Following this initial period, long-term therapy with aspirin and warfarin is suggested.
- This approach balances the need for antithrombotic protection after stenting with anticoagulation requirements.
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