Related Experiment Video
Updated: Jun 22, 2026

03:22
Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
Published on: January 27, 2018
An update on hair restoration therapy
Thomas S Lee1, Timothy J Minton
1Department of Otolaryngology, Upstate Medical University, Syracuse, New York 13210, USA. Leet@upstate.edu
Summary
This review highlights advances in hair restoration surgery. Follicular unit strip surgery remains the standard, while follicular unit extraction (FUE) shows promise with ongoing refinements.
Area of Science:
- Dermatology
- Surgical Innovation
- Hair Restoration Science
Background:
- The field of hair restoration is rapidly evolving.
- Clinicians require up-to-date information on surgical techniques and outcomes.
Purpose of the Study:
- To review recent literature in hair restoration surgery.
- To provide clinicians with insights into current trends and techniques.
Main Methods:
- Literature review of recent studies on hair restoration.
- Analysis of follicular unit transplant surgery and follicular unit extraction (FUE).
Main Results:
- Follicular unit strip surgery remains the established gold standard.
- Follicular unit extraction (FUE) demonstrates increasing success in recent larger series.
- Discussion of hairline design and potential complications in follicular unit transplant surgery.
Conclusions:
- Follicular unit strip surgery is the benchmark for hair replacement.
- Follicular unit extraction (FUE) is a viable alternative with potential for future improvements.
- Further refinements in FUE may enhance its role in hair restoration surgery.
Related Concept Videos
Accessory Structures of the Skin: Hair Growth and Types
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
Multipotency and Niche of Bulge Stem Cell
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
Tissue Renewal without Stem Cells
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
However, failure of such a system...
Stem Cell Therapy for Tissue Regeneration
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

