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Updated: Jun 22, 2026

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation
Published on: June 21, 2016
Gene regulatory networks in embryonic stem cells and brain development
Dhimankrishna Ghosh1, Xiaowei Yan, Qiang Tian
1Institute for Systems Biology, Seattle, Washington 98103, USA.
Abstract:
Embryonic stem cells (ESCs) are endowed with the ability to generate multiple cell lineages and carry great therapeutic potentials in regenerative medicine. Future application of ESCs in human health and diseases will embark on the delineation of molecular mechanisms that define the biology of ESCs. Here, we discuss how the finite ESC components mediate the intriguing task of brain development and exhibit biomedical potentials to cure diverse neurological disorders.
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