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Is urgent coronary artery bypass grafting a safe option in octogenarians? A developing country perspective
Zubair Luqman1, Junaid Ansari, Fahad Javaid Siddiqui
1Department of Surgery, The Aga Khan University Hospital, Karachi 74800, Pakistan. zubair.luqman@aku.edu
Insights
Coronary artery bypass grafting (CABG) in octogenarians shows remarkable outcomes, with most patients experiencing improved quality of life. Urgent CABG demonstrated comparable results to elective procedures in this age group.
Area of Science:
- Cardiology
- Geriatric Medicine
- Cardiac Surgery
Background:
- Increasing life expectancy leads to a larger elderly population requiring advanced medical interventions.
- Coronary artery disease (CAD) management in octogenarians presents unique challenges due to age-related comorbidities.
- Evaluating the safety and efficacy of cardiac surgical procedures in the very elderly is crucial.
Purpose of the Study:
- To assess the outcomes of coronary artery bypass grafting (CABG) specifically in octogenarian patients (aged 80 and above).
- To compare the results of emergent CABG versus elective CABG in this patient cohort.
- To analyze mortality, postoperative complications, and functional status following CABG in octogenarians.
Main Methods:
- Prospective data collection from 31 consecutive octogenarian patients undergoing CABG between January 2006 and December 2008.
- Analysis of key outcomes including mortality, intensive care unit (ICU) and hospital length of stay, surgical priority, and postoperative complications.
- Assessment of functional status and quality of life using the Seattle Angina Questionnaire during follow-up.
Main Results:
- No significant differences were observed in operative and postoperative variables between urgent and elective CABG groups.
- Three in-hospital deaths occurred; 82% of patients were alive at follow-up, with 19 in functional class I or II.
- 90% of patients reported minimal or no disability in daily activities, and 95% expressed satisfaction with their quality of life.
Conclusions:
- Coronary artery bypass grafting can be performed in octogenarian patients with favorable outcomes.
- The procedure leads to significant improvements in patients' functional status and overall quality of life.
- Urgent CABG in octogenarians yields comparable results to elective surgery, suggesting its viability in appropriate cases.
Abstract:
Life expectancy has increased during recent decades leading to a growing number of older population. The objective of this study was to evaluate the outcomes of coronary artery bypass grafting (CABG) in octogenarians and to compare the outcomes of the emergent CABG with elective surgery. Prospectively collected data from 31 consecutive octogenarian patients who underwent CABG between 1 January 2006 and 31 December 2008 were analyzed. Main outcomes of interest included mortality, length of ICU stay, length of hospital stay, priority of surgery, postoperative complications and functional status on follow-up. Fifteen patients were operated on an urgent basis. Patients operated on an urgent basis were in NYHA class III or IV preoperatively (P=0.0016). There were no significant differences in operative and postoperative variables. There were three in-hospital deaths and 23 patients (82%) were alive on follow-up and 19 were in functional class I or II. Quality of life assessment was performed using Seattle Angina Questionnaire and patients reported remarkable improvement in quality of life. Overall, 90% patients were not or slightly disabled in their daily activity. Satisfaction with their current quality of life was reported by 95% of patients. CABG may be performed in octogenarians with remarkable outcomes and improvement in quality of life.
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