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Preparation Of Neovascular Tissues from Human Glioma Tissues for Quantitative Proteomics Analysis of Tumor Angiogenesis
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[Yesterday, today and tomorrow of antiangiogenic therapy]

Elzbieta Adamkiewicz-Drozyńska1, Anna Balcerska, Joanna Stefanowicz

  • 1Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii AM w Gdańsku, ul. Debinki 7, 80-211 Gdańsk, Poland. edrozd@wp.pl

Medycyna Wieku Rozwojowego
|June 18, 2009
PubMed

Insights

Angiogenesis, the formation of new blood vessels, fuels cancer growth. This review covers antiangiogenic agents and metronomic chemotherapy for treating malignancies, including pediatric cases.

Area of Science:

  • Oncology
  • Vascular Biology

Context:

  • Angiogenesis is crucial for tumor growth and metastasis.
  • Understanding angiogenesis is key for developing novel cancer therapies.

Purpose:

  • To review the role of angiogenesis in cancer.
  • To discuss antiangiogenic agents and metronomic chemotherapy.
  • To present clinical experiences and study results.

Summary:

  • Discusses the role of angiogenesis in neoplasm development and regulation.
  • Details current antiangiogenic agents in oncological treatment.
  • Highlights metronomic chemotherapy for inhibiting tumor angiogenesis, including pediatric applications and combination therapies.

Impact:

  • Provides insights into current and emerging antiangiogenic strategies.
  • Informs on the potential of metronomic chemotherapy in cancer treatment.
  • Supports the development of targeted therapies for malignancies.

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