Related Experiment Video
Updated: Jun 22, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Risk factors and treatment for obstructive sleep apnea amongst obese children and adults
1Discipline of Paediatrics, University of Adelaide, Women's and Children's Hospital, South Australia, Australia. mark.kohler@adelaide.edu.au
Insights
Obesity is linked to obstructive sleep apnea (OSA), with factors like age and anatomy influencing risk. Weight-loss strategies show promise for treating OSA in obese individuals.
Area of Science:
- Sleep Medicine
- Obesity Research
- Respiratory Health
Background:
- Obesity is a growing global health concern.
- Obstructive sleep apnea (OSA) is a common sleep disorder.
- The relationship between obesity and OSA requires further investigation.
Purpose of the Study:
- To review evidence on the association between obesity and OSA.
- To identify risk factors for OSA in obese patients.
- To summarize treatment strategies for OSA in obese individuals.
Main Methods:
- Systematic literature review.
- Analysis of recent research findings.
- Synthesis of evidence on predisposing factors and treatments.
Main Results:
- Obesity predisposes individuals to OSA through factors like sex, age, upper airway structure, and ethnicity.
- Weight-reduction strategies, both invasive and noninvasive, are effective in managing OSA in obese adults and children.
- The direct association between body mass and airway obstruction needs cautious interpretation.
Conclusions:
- Obesity's role in OSA predisposition varies among subgroups, particularly adults with specific craniofacial morphology.
- Standard OSA treatments may be less effective in obese patients.
- Weight-reduction strategies are crucial for optimal OSA management in obese individuals, with invasiveness tailored to patient needs.
Purpose Of Review:
The purpose of this review is to summarize the evidence for the association between obesity and obstructive sleep apnea (OSA), as well as predisposing risk factors and treatment strategies for OSA amongst obese patients.
Recent Findings:
Recent findings highlight a number of factors including sex, age, upper airway structure and ethnicity, which may predispose patients to OSA when obese. Both invasive and noninvasive weight-reduction strategies also show positive signs of being an effective means to reduce or remediate OSA amongst obese adults and children.
Summary:
In view of recent findings, a direct association between body mass and upper airway obstruction should be viewed with caution. Obesity may play a more significant role in the predisposition to OSA amongst particular subgroups of the population, such as adults, and those with particular craniofacial and upper airway morphology. Healthcare prioritization and requirements may be more substantial for such groups. Further, commonly used treatment methods for OSA (such as adenotonsillectomy for children and continuous positive airway pressure for adults) may be less effective for obese individuals. Weight-reduction strategies appear important for an optimal outcome, and such strategies may be more or less invasive depending on the severity of obesity, OSA or both, and other patient complications.
Related Concept Videos
Sleep Apnea
The condition is more prevalent among...
Obesity
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Other Pulmonary Disorders
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
