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Updated: Jun 22, 2026

Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers

Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers

Published on: May 5, 2016

Digital fluorescent pH sensors.

Seiichi Uchiyama¹, Yumi Makino

¹Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan. seiichi@mol.f.u-tokyo.ac.jp

Chemical Communications (Cambridge, England)

|June 18, 2009

Summary

New polymeric sensors provide a digital fluorescence response to changes in aqueous solution pH. This advancement offers a precise method for monitoring pH levels in various applications.

Area of Science:

Polymer Science
Analytical Chemistry
Sensor Technology

Background:

Accurate pH monitoring is crucial in diverse scientific and industrial fields.
Traditional pH measurement methods can be complex or limited in certain environments.

Purpose of the Study:

To develop novel polymeric sensors capable of detecting pH variations.
To achieve a digital-type fluorescence response for simplified pH indication.

Main Methods:

Design and synthesis of specialized polymers for sensor fabrication.
Integration of polymers into sensor platforms.
Characterization of sensor performance using fluorescence spectroscopy and pH titration.

Main Results:

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The developed polymeric sensors exhibited a distinct digital-type fluorescence output.

The fluorescence response directly correlated with changes in the aqueous solution's pH.

High sensitivity and specificity of the sensors were demonstrated.

Conclusions:

Polymeric sensors offer a promising platform for digital pH sensing.
The digital fluorescence response simplifies pH signal interpretation.
These sensors have potential applications in environmental monitoring, chemical analysis, and diagnostics.