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Updated: Jun 22, 2026

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
Published on: October 13, 2016
Amyotrophic lateral sclerosis and ocular flutter
Michelle S Balaratnam1, Guy D Leschziner, Barry M Seemungal
1Neuromuscular Unit, West London Neurosciences Centre, Charing Cross Hospital, London, UK.
Abstract:
A previously unreported association of amyotrophic lateral sclerosis and ocular flutter is presented. It is hypothesized that initial loss of brainstem inhibitory interneurons resulted in disinhibition of burst interneurons and that the ocular flutter subsequently disappeared as burst interneurons also became affected by the disease process. The association adds clinical evidence of involvement of brainstem interneurons to other evidence of involvement of neurons other than motor neurons in the disease process.
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