[The controversial aspects of granulomatous inflammation]

The necessity of a new concept of nontumorous benign monocytosis is brought forward for discussion. It is suggested to include into the group of "granulomatous inflammation" chronic inflammation with epithelioid cell granulomas. Species peculiarities of rodents (mice and rats) are underlined, i.e. their capacity to form liver macrophagal proliferates as a response to various stimuli including antigenic and acute infectious ones.