Related Experiment Video
Updated: Jun 22, 2026
Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
Published on: June 6, 2025
A crowdsourcing evaluation of the NIH chemical probes
Tudor I Oprea1, Cristian G Bologa, Scott Boyer
1University of New Mexico Center for Molecular Discovery, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA. toprea@salud.unm.edu
Abstract:
Between 2004 and 2008, the US National Institutes of Health Molecular Libraries and Imaging initiative pilot phase funded 10 high-throughput screening centers, resulting in the deposition of 691 assays into PubChem and the nomination of 64 chemical probes. We crowdsourced the Molecular Libraries and Imaging initiative output to 11 experts, who expressed medium or high levels of confidence in 48 of these 64 probes.
