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Updated: Jun 22, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
10:10

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Published on: March 31, 2019

The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting

Mary E Donohoe1, Susana S Silva, Stefan F Pinter

  • 1Howard Hughes Medical Institute, USA.

Nature
|June 19, 2009
PubMed
Summary

Oct4, a key pluripotency factor, initiates X-chromosome inactivation (XCI) by regulating homologous chromosome pairing and counting. This discovery reveals Oct4

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