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Related Concept Videos

Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
Polytene Chromosomes02:04

Polytene Chromosomes

Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
Replicative Cell Senescence02:15

Replicative Cell Senescence

Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds the telomeric...
Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
M-Cdk Drives Transition Into Mitosis02:15

M-Cdk Drives Transition Into Mitosis

Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...
M-Cdk Drives Transition Into Mitosis02:15

M-Cdk Drives Transition Into Mitosis

Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
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Related Experiment Video

Updated: Jun 22, 2026

A Protocol to Acquire the Degenerative Tenocyte from Humans
09:25

A Protocol to Acquire the Degenerative Tenocyte from Humans

Published on: June 9, 2018

NKT cells turn ten.

Peter D Burrows1, Mitchell Kronenberg, Masaru Taniguchi

  • 1University of Alabama at Birmingham, Birmingham, Alabama, USA. peterb@uab.edu

Nature Immunology
|June 19, 2009
PubMed
Summary
This summary is machine-generated.

Ten years ago, a workshop on natural killer T cells (NKT cells) spurred significant growth in this research area. This field continues to expand rapidly.

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Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells
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Last Updated: Jun 22, 2026

A Protocol to Acquire the Degenerative Tenocyte from Humans
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Published on: June 9, 2018

Interview: Glycolipid Antigen Presentation by CD1d and the Therapeutic Potential of NKT cell Activation
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Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells
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Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells

Published on: February 2, 2011

Area of Science:

  • Immunology
  • Cellular Biology

Background:

  • The field of natural killer T (NKT) cell research has experienced substantial growth over the past decade.
  • The inaugural workshop on NKT cells marked a pivotal moment, catalyzing advancements in understanding their function and therapeutic potential.

Framework:

  • NKT cells represent a unique lineage of immune cells bridging innate and adaptive immunity.
  • Their distinct properties, including rapid cytokine production and ability to modulate immune responses, are key areas of investigation.

Implementation:

  • Research efforts have focused on elucidating NKT cell subsets and their specific roles in various physiological and pathological conditions.
  • Studies explore the activation pathways and signaling mechanisms governing NKT cell responses.

Implications:

  • Continued research into NKT cells holds promise for developing novel immunotherapies for cancer, infectious diseases, and autoimmune disorders.
  • Understanding NKT cell biology is crucial for harnessing their potential in clinical applications and advancing immune-based treatments.