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Updated: Jun 22, 2026

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In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Small (< or = 4 cm) cortical renal tumors: characterization with multidetector CT
Ghazi Alshumrani1, Martin O'Malley, Sangeet Ghai
1Department of Medical Imaging, University of Toronto, Toronto, Canada.
Abdominal Imaging
|June 19, 2009
Summary
Multidetector CT can predict small solid renal tumor pathology. Papillary renal cell carcinomas show less enhancement than clear cell renal cell carcinomas and oncocytomas on CT scans.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Solid renal tumors under 4 cm pose diagnostic challenges.
- Accurate preoperative pathology prediction is crucial for treatment planning.
Purpose of the Study:
- To evaluate if multidetector computed tomography (CT) findings can predict the pathology of small solid renal tumors (< or = 4 cm).
Main Methods:
- Retrospective analysis of 47 small renal tumors in 46 patients.
- Triphasic renal CT scans were reviewed by two radiologists blinded to pathology.
- Morphologic and enhancement features were correlated with surgical pathology.
Main Results:
- Tumor types included clear cell renal cell carcinoma (55%), oncocytoma (19%), and papillary renal cell carcinoma (15%).
- Heterogeneity was common in clear cell RCC (88%) and oncocytoma (67%).
- Absolute nephrographic phase enhancement was significantly lower in papillary RCC (16 HU) compared to clear cell RCC (65 HU) and oncocytoma (80 HU).
Conclusions:
- Absolute nephrographic phase enhancement of <= 32 HU effectively distinguishes papillary renal cell carcinomas from clear cell renal cell carcinomas and oncocytomas.
- CT-based enhancement patterns aid in differentiating common small renal tumor subtypes.
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