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Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

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Related Experiment Video

Updated: Jun 22, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Does eczema lead to asthma?

John A Burgess1, Adrian J Lowe, Melanie C Matheson

  • 1Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Carlton, Victoria, Australia. j.burgess@pgrad.unimelb.edu.au

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
|June 23, 2009
PubMed
Summary
This summary is machine-generated.

Eczema may causally lead to asthma and allergic rhinitis, challenging previous views. Early eczema intervention could prevent these later respiratory conditions and improve public health.

Related Experiment Videos

Last Updated: Jun 22, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Area of Science:

  • Immunology
  • Dermatology
  • Allergology

Background:

  • The relationship between eczema, asthma, and allergic rhinitis is debated.
  • These conditions share genetic and environmental risk factors.
  • Current understanding suggests they may be unrelated or sequential.

Purpose of the Study:

  • To review the link between eczema, asthma, and allergic rhinitis.
  • To explore the role of the atopic march and skin barrier.
  • To propose a causal relationship with eczema as the initial step.

Main Methods:

  • Literature review focusing on the atopic march, skin barrier function, and eczema genetics.
  • Analysis of existing research to identify a biological pathway.
  • Synthesis of evidence to support a causal link.

Main Results:

  • A plausible biological pathway suggests eczema initiates the atopic march.
  • Eczema may be the first step leading to asthma and/or allergic rhinitis over time.
  • Recent genetic findings support a stronger connection.

Conclusions:

  • The relationship between eczema and subsequent respiratory disorders is likely causal.
  • Eczema management could potentially prevent asthma development.
  • Intervention studies are needed to confirm causality and guide public health strategies.