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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
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Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Published on: June 27, 2025

Trauma in pregnancy.

Haywood L Brown1

  • 1From the Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina.

Obstetrics and Gynecology
|June 24, 2009
PubMed
Summary
This summary is machine-generated.

Acute traumatic injuries pose significant risks to pregnant individuals and fetuses. Prompt, coordinated medical care, including imaging and potential perimortem cesarean delivery, is crucial for optimal outcomes in trauma patients.

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Published on: December 22, 2023

Area of Science:

  • Obstetrics and Gynecology
  • Trauma Surgery
  • Emergency Medicine

Background:

  • Acute traumatic injuries are a leading cause of maternal and fetal morbidity and mortality in the US.
  • Motor vehicle accidents, violence, and assault are primary causes of traumatic injury during pregnancy.
  • Inadequate restraint use and domestic abuse significantly increase risks.

Purpose of the Study:

  • To outline management strategies for acute traumatic injuries in pregnant individuals.
  • To emphasize the importance of prompt maternal assessment and coordinated care.
  • To highlight specific interventions and considerations for maternal-fetal well-being.

Main Methods:

  • Review of existing literature and clinical guidelines on managing trauma in pregnancy.
  • Emphasis on comprehensive maternal assessment and multidisciplinary team approach.
  • Discussion of imaging, surgical interventions, and perimortem cesarean delivery.

Main Results:

  • Motor vehicle accidents are the leading cause of injury-related maternal death.
  • Blunt abdominal trauma increases placental abruption risk; penetrating trauma poses direct fetal injury risk.
  • Early consideration of perimortem cesarean delivery is vital when fetal viability is a concern.

Conclusions:

  • A coordinated, multidisciplinary approach involving obstetricians is essential for optimal maternal and fetal outcomes.
  • Imaging should not be delayed due to radiation concerns; perimortem cesarean delivery should be considered early.
  • Thorough documentation and ongoing maternal-fetal observation are critical post-stabilization.