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Related Experiment Video

Updated: Jun 22, 2026

Optogenetic Functional MRI
06:06

Optogenetic Functional MRI

Published on: April 19, 2016

Opening up optical fibres.

Felicity M Cox, Richard Lwin, Maryanne C J Large

    Optics Express
    |June 24, 2009
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel optical fiber for real-time chemical and biosensing. The unique design allows direct core functionalization and sensing, enabling new applications in evanescent wave spectroscopy.

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    Area of Science:

    • Optoelectronics
    • Chemical Sensing
    • Materials Science

    Background:

    • Conventional microstructured optical fibers (MOFs) have limitations in direct core functionalization and real-time sensing.
    • Limited accessibility to the optical core restricts advanced applications in chemical and biological detection.

    Purpose of the Study:

    • To present a novel laterally accessible MOF design.
    • To demonstrate its potential for real-time chemical sensing and biosensing applications.
    • To showcase core functionalization without cladding interference.

    Main Methods:

    • Fabrication of a PMMA-based MOF with an open cladding hole.
    • Demonstration of evanescent wave absorption spectroscopy.
    • Utilizing Bromothymol Blue as a pH indicator.

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    Last Updated: Jun 22, 2026

    Optogenetic Functional MRI
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    Main Results:

    • Successful fabrication of the laterally accessible MOF.
    • Experimental validation of its use as a pH sensor.
    • Demonstrated real-time sensing capabilities via evanescent wave spectroscopy.

    Conclusions:

    • The developed optical fiber design enables unprecedented real-time chemical and biosensing.
    • It offers a versatile platform for core functionalization and advanced optical sensing.
    • This technology opens new avenues for in-situ monitoring and diagnostics.