Influence of hydroxyapatite crystallinity on the growth of keratinocytes

Dental implantology is a field, which has made a great progression recently. The main task nowadays is to shorten the healing period and so improve the comfort for the patients. One possibility how to full fil this task is to coat the surface of the implant. Very promising material seems to be hydroxyapatite, which is a natural component of human body and suitable method is the pulsed laser deposition. In our study we tried to evaluate difference between crystalline and amorphous hydroxyapatite coated dental implants from the biological point of view. We found that the cells were able to adhere to all of our studied samples. The worst proliferation of fibroblasts was found on the amorphous coating, whereas the adhesion was fully comparable with other surfaces. The level of keratinocyte differentiation was the same on both of the studied surfaces.