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Apexification: the beginning of its end
1Department of Endodontics, Prosthodontics and Operative Dentistry, College of Dental Surgery, University of Maryland, Baltimore, MD 21201, USA. ghuang@umaryland.edu
Apexification is a dental procedure for immature teeth lacking pulp vitality. New revitalization and tissue engineering approaches promise to regenerate pulp tissue, potentially making apexification less necessary for future treatments.
Area of Science:
- Dentistry
- Regenerative Medicine
Background:
- Apexification is a long-standing treatment for immature permanent teeth with nonvital pulps.
- Current apexification methods, including mineral trioxide aggregate barriers, have not significantly improved outcomes like apical maturation or root thickness.
Purpose of the Study:
- To overview the emerging concept of pulp revitalization for treating immature, nonvital teeth.
- To discuss recent research in pulp tissue engineering and regeneration for dental applications.
Main Methods:
- Review of current literature on apexification and regenerative endodontics.
- Exploration of novel approaches like pulp revitalization and tissue engineering.
Main Results:
- Pulp revitalization aims to achieve tissue generation within the root canal, promoting continued root development.
- Pulp/dentine regeneration through tissue engineering offers potential for regrowing vital pulp tissue.
Conclusions:
- Emerging regenerative strategies show promise for continued root growth and maturation in immature pulpless teeth.
- These advancements may reduce the future need for traditional apexification procedures.
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