Mitral regurgitation associated with mitral annular dilation in patients with lone atrial fibrillation: an echocardiographic study
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Updated: Jun 22, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
Takashi Kihara1, A Marc Gillinov, Kunitsugu Takasaki
1Department of Cardiovascular Medicine, The Cleveland Clinic, Cleveland, Ohio 90048, USA. shiotat@cshs.org
Background:
Whether and how lone atrial fibrillation (AF) is associated with functional mitral regurgitation (MR) remain unclear.
Method:
We studied 12 lone AF patients without left ventricular (LV) dysfunction and/or dilatation, who underwent mitral valve annuloplasty for functional mitral regurgitation (MR). Ten lone AF patients without MR served as controls.
Results:
Lone AF Patients with MR had a greater mitral valve annular area and left atrial area than those without MR. There were no differences in LV volumes or LV ejection fraction.
Conclusions:
Therefore, we concluded that left atrial dilation and corresponding mitral annular dilation may cause MR in lone AF patients without LV dysfunction and/or dilatation.
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