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Related Concept Videos

The Contractile Ring02:15

The Contractile Ring

Contractile rings are composed of microfilaments and are responsible for separating the daughter cells during cytokinesis. Contractile ring assembly proceeds along with other cell cycle events; however, very few mechanistic details are known about the timing and coordination of the contractile rings with the cell cycle.
A small GTPase, RhoA, controls the function and assembly of the contractile ring. RhoA belongs to the Ras superfamily of proteins. The activation of formins by RhoA promotes...
The Contractile Ring02:15

The Contractile Ring

Contractile rings are composed of microfilaments and are responsible for separating the daughter cells during cytokinesis. Contractile ring assembly proceeds along with other cell cycle events; however, very few mechanistic details are known about the timing and coordination of the contractile rings with the cell cycle.
A small GTPase, RhoA, controls the function and assembly of the contractile ring. RhoA belongs to the Ras superfamily of proteins. The activation of formins by RhoA promotes...
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Fascicle Arrangement in Skeletal Muscles01:25

Fascicle Arrangement in Skeletal Muscles

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Mitral Stenosis I: Introduction01:22

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...

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Related Experiment Video

Updated: Jun 22, 2026

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy
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O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy

Published on: October 6, 2022

Constriction ring syndrome.

Eileen Bernal1, John C Oeltjen

  • 1Dewitt Daughtry Department of General Surgery, University of Miami, Miami, FL 33136, USA.

The Journal of Craniofacial Surgery
|June 26, 2009
PubMed
Summary
This summary is machine-generated.

Constriction ring syndrome is a congenital anomaly. Treatment focuses on functional recovery and preventing complications due to its unknown cause, rather than preventing the syndrome itself.

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Last Updated: Jun 22, 2026

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Area of Science:

  • Medical Genetics
  • Developmental Biology
  • Pediatric Surgery

Background:

  • Constriction ring syndrome (CRS) is a congenital anomaly with potentially severe outcomes.
  • The exact etiology of CRS remains unknown, complicating preventative strategies.
  • Current management focuses on mitigating consequences and improving function.

Purpose of the Study:

  • To review current theories on the etiology of constriction ring syndrome.
  • To outline the clinical features and associated defects in CRS.
  • To discuss the surgical management approaches for constriction ring syndrome.

Main Methods:

  • Literature review of existing research on constriction ring syndrome.
  • Analysis of etiological theories, clinical presentations, and treatment modalities.
  • Synthesis of information on diagnosis and surgical interventions.

Main Results:

  • Multiple theories exist regarding the cause of CRS, but none are definitively proven.
  • CRS presents with characteristic limb constriction and can be associated with other congenital defects.
  • Surgical intervention is crucial for functional recovery and preventing long-term sequelae.

Conclusions:

  • Understanding the diverse theories of CRS etiology is important for future research.
  • Comprehensive assessment of associated anomalies is vital for effective patient management.
  • Timely and appropriate surgical management significantly improves outcomes for patients with constriction ring syndrome.