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Moraxella (Branhamella) catarrhalis.

A Verghese1, S L Berk

  • 1Texas Tech Regional Academic Health Center, El Paso.

Infectious Disease Clinics of North America
|September 1, 1991
PubMed
Summary
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Moraxella catarrhalis is a significant pathogen causing lower respiratory tract infections, especially in patients with chronic lung disease. Most strains now produce beta-lactamase, a recently acquired trait.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Moraxella catarrhalis is increasingly recognized as a pathogen in lower respiratory tract infections.
  • Clinical strains commonly exhibit beta-lactamase production, a recently acquired characteristic.
  • The organism is frequently implicated in exacerbations of chronic bronchitis.

Purpose of the Study:

  • To review the clinical significance of Moraxella catarrhalis in respiratory infections.
  • To highlight the prevalence and characteristics of beta-lactamase producing strains.
  • To describe the clinical syndromes associated with Moraxella catarrhalis infections.

Main Methods:

  • Literature review of clinical studies and case reports.
  • Analysis of epidemiological data on Moraxella catarrhalis infections.

Related Experiment Videos

  • Review of antimicrobial resistance patterns, focusing on beta-lactamase production.

    • Main Results:

    • Moraxella catarrhalis is a common cause of chronic bronchitis exacerbations, particularly in elderly patients with lung disease.
    • Beta-lactamase production is a prevalent trait in current clinical isolates.
    • Pneumonia, suppurative complications, and bacteremia are less frequent manifestations.

    Conclusions:

    • Moraxella catarrhalis is a significant respiratory pathogen, especially in individuals with underlying chronic lung conditions.
    • The widespread beta-lactamase production necessitates consideration in treatment strategies.
    • While chronic bronchitis exacerbations are common, severe complications are rare.