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Microalbuminuria among type-2 diabetes mellitus patients in Pokhara, Nepal

M Sigdel1, N Rajbhandari, S Basnet

  • 1The School of Pharmaceuticals and Biomedical Sciences, Pokhara University, Kaski, Nepal. _manojsigdel11@hotmail.com

Nepal Medical College Journal : NMCJ
|June 30, 2009
PubMed

Insights

Microalbuminuria, an early sign of diabetic kidney disease, is prevalent in 45.5% of type 2 diabetes patients. Early screening for microalbuminuria is crucial for managing cardiovascular risks and preventing kidney disease progression.

Area of Science:

  • Endocrinology
  • Nephrology
  • Cardiology

Background:

  • Microalbuminuria signifies early diabetic nephropathy and cardiovascular disease risk.
  • Type 2 diabetes is a growing global health concern.
  • Early detection of complications is vital for patient outcomes.

Purpose of the Study:

  • To determine the prevalence of microalbuminuria in type 2 diabetes patients.
  • To investigate the association between microalbuminuria and cardiovascular risk factors.
  • To highlight the importance of screening for early intervention.

Main Methods:

  • Cross-sectional analysis of 143 type 2 diabetes patients.
  • Assessment of microalbuminuria and overt proteinuria.
  • Evaluation of cardiovascular risk factors including blood pressure, lipid profile, and diabetes duration.

Main Results:

  • Prevalence of microalbuminuria was 45.5%; overt proteinuria was 11.2%.
  • Microalbuminuria correlated significantly with higher blood pressure and longer diabetes duration.
  • Lower high-density lipoprotein levels were observed in patients with microalbuminuria.

Conclusions:

  • A high prevalence of microalbuminuria exists in type 2 diabetes patients.
  • Microalbuminuria is associated with key cardiovascular risk factors like hypertension.
  • Screening for microalbuminuria is essential for preventing diabetic nephropathy and cardiovascular complications.

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