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Updated: Jun 22, 2026

Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights
Published on: October 13, 2023
Brainstem involvement in Sjögren's syndrome-related sensory neuronopathy
Alfredo Damasceno1, Marcondes C França, Verônica A Zanardi
1Departments of Neurology, School of Medicine, State University of Campinas (UNICAMP), Campinas, Brazil. alfredodamasceno@hotmail.com
Background And Purpose:
Sensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Magnetic resonance imaging (MRI) studies have shown abnormalities limited to T2-weighted high signal intensity in the posterior columns.
Methods And Results:
A 65-year-old woman with Sjögren syndrome had slowly progressive unsteadiness of gait and limb paresthesias. A blink reflex examination suggested a paramedian brainstem lesion, confirmed by MRI.
Conclusions:
Sjögren's syndrome-related SN may be associated with a more diffuse immune-mediated aggression, involving also the brainstem, and leading to some of the blink reflex abnormalities observed in nonparaneoplastic SN.
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