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Updated: Jun 22, 2026
Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model
Published on: April 18, 2015
Liver perfusion with dynamic multidetector-row computed tomography as an objective method to evaluate the efficacy of
Sandra Pauls1, Andreas Gabelmann, Wolfgang Heinz
1Department of Diagnostic and Interventional Radiology, University Hospitals of Ulm, Ulm, Germany. sandra.pauls@uni-ulm.de
Abstract:
A total of 24 liver metastases of colorectal cancer were evaluated by dynamic multiphasic CT. Under chemotherapy, follow-up examinations were performed every 3 months. The tumor marker CEA before vs. after chemotherapy correlated with the mean contrast enhancement within the margin of metastases. The total size of metastases correlated with the size of central necrosis as well as with the size of marginal contrast enhancement. CT is able to quantify perfusion and local activity of liver metastases to determine the efficacy of chemotherapy.
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