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Disorders of the Male Reproductive System

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Related Experiment Video

Updated: Jun 22, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Screening for prostate cancer.

Otis W Brawley¹, Donna P Ankerst, Ian M Thompson

¹American Cancer Society, Atlanta, GA, USA.

CA: a Cancer Journal for Clinicians

|July 1, 2009

Summary

This summary is machine-generated.

Prostate cancer screening with PSA tests has uncertain benefits. New risk assessment tools and finasteride may help men manage their prostate cancer risk.

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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

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Last Updated: Jun 22, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Area of Science:

Urology
Oncology
Public Health

Background:

Prostate cancer affects 1 in 6 US men.
Prostate-specific antigen (PSA) screening since the 1980s increased diagnosis rates.
The impact of PSA screening on mortality versus improved treatments remains unclear.

Purpose of the Study:

To evaluate the effectiveness of prostate cancer screening.
To discuss risk assessment methods and potential interventions.

Main Methods:

Review of recent large randomized trials on PSA screening.
Assessment of risk-stratification tools integrating multiple factors.
Consideration of finasteride's role in managing screening-detected prostate cancer.

Main Results:

Recent trials suggest any benefit from PSA screening is small.
Integrated risk assessment tools are available for personalized evaluation.
Finasteride may reduce prostate cancer risk in screened men.

Conclusions:

Individualized risk assessment is crucial for prostate cancer screening decisions.
The benefits of widespread PSA screening are questionable.
Finasteride presents a potential chemopreventive option for certain men.