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Colorimetric Assessment of Deiodinase 1 Activity in Human Liver Microsomes Using the Sandell-Kolthoff Reaction

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Current iodine status in Turkey.

M F Erdoğan¹, K Ağbaht, T Altunsu

¹Department of Endocrinology and Metabolism, Faculty of Medicine, Ankara University, Ankara, Turkey. murat.erdogan@temd.org.tr

Journal of Endocrinological Investigation

|July 1, 2009

Summary

Turkey

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Area of Science:

Public Health
Nutritional Science
Endocrinology

Background:

Iodine deficiency remains a significant global public health concern.
Monitoring iodine status is crucial for effective public health interventions.
Previous surveys indicated substantial iodine deficiency in Turkey.

Purpose of the Study:

To assess the current nationwide iodine status in Turkey.
To determine urinary iodine concentrations (UIC) and household salt iodine content.
To conduct a follow-up monitoring study in urban areas.

Main Methods:

A nationwide school-based survey was conducted in 2007.
Multistage 'proportionate to population size' (PPS) cluster sampling was employed.
Urinary iodine concentrations and household salt iodine content were analyzed in 900 school-age children.

Main Results:

Median urinary iodine concentration (UIC) was 107 microg/l, with significant urban-rural disparities (147 microg/l urban vs. 42 microg/l rural).
27.8% of the population exhibited moderate to severe iodine deficiency (ID).
Adequately iodized salt was found in 56.5% of households, correlating with UIC levels.

Conclusions:

While iodine deficiency has improved significantly since 1997 and 2002, it persists in 27.8% of the Turkish population.
Iodine deficiency has been eliminated in most urban areas, but remains a concern in rural regions.
Targeted public health programs are needed for rural areas and specific geographical regions to address persistent iodine deficiency.