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[Perioperative management of chronic medication: to withhold, continue or intensify?]
Giovanna Lurati Buse1, Evelyne Bucher, Manfred D Seeberger
1Departement Anästhesie, Universitätsspital Basel.
Insights
Continue chronic medications until the day before surgery for optimal patient stability. Preoperative assessment should ensure existing treatments, like beta-blockers and statins, are optimized, avoiding new medication initiation.
Area of Science:
- Cardiology
- Endocrinology
- Pharmacology
Context:
- Optimizing patient condition for surgery is crucial.
- Chronic medications should be continued preoperatively.
- Preoperative assessment evaluates existing medical treatments.
Purpose:
- To guide the continuation and optimization of chronic medications before elective surgery.
- To highlight the importance of assessing cardiological, diabetic, and thyroid treatments.
- To advise against initiating new medications without a prior chronic indication.
Summary:
- Chronic medications should generally be continued until the day before surgery.
- Preoperative evaluation should focus on optimizing existing treatments for conditions like hypertension, diabetes, and thyroid dysfunction.
- Discontinuation or initiation of certain medications, such as antiplatelets and anticoagulants, requires careful risk-benefit assessment.
Impact:
- Ensures patients undergo surgery in the most stable condition.
- Reduces perioperative complications by optimizing chronic disease management.
- Provides a clear framework for preoperative medication management, enhancing surgical outcomes.
Abstract:
All patients should undergo surgical procedures in the most stable and favourable condition with a continuation of chronic medication. Accordingly, this medication should be continued until the day before surgery in most patients. The preoperative period should be used to evaluate the completeness and quality of the medical treatment. Are all patient with cardiological indications for beta-receptor blocking agents, ACE-inhibitors and statins treated with these drugs? Is diabetes being adequately treated? Are the doses of the medication for the treatment of thyroid dysfunction within the optimal range? If there is room for improvement, adjustments should be done cautiously and well in advance. In contrast, there are no recognised situations in which a medication should be started preoperatively in the absence of a pre-established chronic indication. Management of antiplatelet agents and cumarins requires careful consideration. The hazards of continuing and withholding treatment must be evaluated. In patients who have suffered a cardiovascular event and/or have undergone (coronary) revascularisation, elective surgery must be delayed for weeks or months depending on the circumstances and the devices used.
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