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Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
Published on: May 12, 2023
[Study on the optimal extracion craft of Xiaochuang gel by central composite design-response surface methodology]
Wei-Wei Chen1, Dong-Ying Xu, Chao-Cheng Deng
1Guangxi Traditional Chinese Medical University, Nanning 530001, China. weiwei690413@eyou.com
Objective:
To optimize the extraction craft of Xiaochuang gel by central composite design-response surface methodology.
Methods:
The main influential factors of extraction effect included the quantity of ethanol, the concentration of ethanol and the extraction time. The conditions of the extraction were evaluated by the yield of the extracts and the total content of rheum emodin and chrysophanol. The optimal extraction craft of Xiaochuang gel was chosen by central composite design-response surface methodology.
Results:
The optimal conditions were extracting two times, two hours each time with ten volume multiples of 60% ethanol.
Conclusions:
It is simple, convenient and highly predictive to optimize the extraction craft of Xiaochuang gel by central composite design-response surface methodology.
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Methods of Medium Optimization
Response Surface Methodology
The process of RSM involves several key steps:

