[Heart rate variability in chronic pulmonary heart]

Area of Science:

• Cardiology
• Pulmonology
• Autonomic Nervous System Research

Background:

• Persistent asthma can lead to cardiovascular complications.
• Pulmonary heart disease is a serious complication of chronic lung diseases like asthma.
• Early detection of cardiac involvement in asthma is crucial for timely intervention.

Purpose of the Study:

• To investigate early signs of cardiovascular dysregulation in patients with persistent asthma.
• To explore the relationship between peripheral vegetative regulation, autonomous cardioneuropathy, and pulmonary heart disease development.
• To identify early manifestations of pulmonary heart in bronchial asthma patients.

Main Methods:

• Rhythmocardiography using a high-resolution KAP-RK-01 Mikor system was employed.
• Analysis of cardiac rhythm variability was performed on 265 patients.
• Correlation between autonomous cardioneuropathy and structural cardiac changes was assessed.

Main Results:

• Cardiac rhythm variability indicated impaired peripheral vegetative regulation of sinus node chronotropic function.
• Functional insufficiency of pacemaker cells was observed.
• Early symptoms of chronic pulmonary heart in asthma patients correlated with autonomous cardioneuropathy and structural cardiac changes.

Conclusions:

• Peripheral vegetative dysregulation and pacemaker insufficiency are key pathogenetic components of cardiac disorders in bronchial asthma.
• Autonomous cardioneuropathy, with suppressed sympathetic and parasympathetic regulation, is an early manifestation of pulmonary heart development.
• This study highlights the importance of assessing cardiovascular autonomic function in asthma management.