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Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

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Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
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Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
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A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
05:39

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis

Published on: November 30, 2021

Neutropenic enterocolitis.

Brant W Ullery1, Fredric M Pieracci, John R M Rodney

  • 1Department of Surgery, Weill Cornell Medical College, New York, New York 10021, USA.

Surgical Infections
|July 2, 2009
PubMed
Summary
This summary is machine-generated.

Neutropenic enterocolitis (typhilitis) is a serious gastrointestinal infection in neutropenic patients. Early detection and individualized care, including medical or surgical options, are crucial for managing this complex condition.

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Area of Science:

  • Gastroenterology
  • Oncology
  • Infectious Diseases

Background:

  • Neutropenic enterocolitis (typhilitis) is a common GI infection in neutropenia.
  • Its diagnosis and management are variable due to rarity, terminology, and non-specific symptoms.

Purpose of the Study:

  • To review the literature on neutropenic enterocolitis.
  • To clarify diagnosis and management strategies for this condition.

Main Methods:

  • Literature review of English-language publications.

Main Results:

  • Incidence may be 5% or more in chemotherapy patients; increasing reports in non-chemotherapy cases.
  • Mortality rates range from 30% to 50%.
  • Computed tomography is key for diagnosis; management is individualized (medical or surgical).

Conclusions:

  • Neutropenic enterocolitis is a heterogeneous disease with variable severity.
  • High suspicion is needed for patients with fever and abdominal pain during neutropenia.
  • Early detection allows nonoperative management, but surgery is vital for complications.