Related Experiment Video
Updated: Jun 22, 2026

Evaluation of Blood Lactate and Plasma Insulin During High-intensity Exercise by Antecubital Vein Catheterization
Published on: May 18, 2018
Blood glucose minimum predicts maximal lactate steady state on running
R C Sotero1, E Pardono, R Landwehr
1Department of Physical Education, Catholic University of Brasilia, Distrito Federal, Brazil.
The running speed at glucose minimum (GM) accurately predicts the maximal lactate steady state (MLSS) in active individuals. This finding offers practical applications for exercise prescription and training intensity determination.
Area of Science:
- Exercise Physiology
- Sports Science
- Metabolic Adaptations
Background:
- Maximal lactate steady state (MLSS) is a key indicator of endurance capacity.
- Identifying reliable predictors of MLSS is crucial for effective exercise prescription.
- The relationship between glucose metabolism during exercise and MLSS requires further investigation.
Purpose of the Study:
- To determine if the running speed at glucose minimum (GM) can predict MLSS in physically active men.
- To compare GM speed with lactate minimum (LM) speed and MLSS.
- To assess the practical applicability of GM speed for exercise intensity guidelines.
Main Methods:
- Thirteen physically active men performed a 1600-m time trial, incremental running tests to identify GM and LM speeds, and constant intensity exercise sessions to determine MLSS.
- Statistical analyses included repeated measures ANOVA and Bland and Altman plots.
- Speeds were analyzed in relation to 1600-m time trial performance.
Main Results:
- No significant differences were found between running speeds for GM, LM, and MLSS.
- High correlations were observed between GM and LM (r=0.984), GM and MLSS (r=0.947), and LM and MLSS (r=0.961).
- Bland and Altman plots indicated good agreement between GM, LM, and MLSS.
Conclusions:
- Running speed at GM is a reliable predictor of MLSS in physically active individuals.
- GM speed, occurring at approximately 84.4% of 1600-m speed, has practical implications for exercise prescription.
- The findings support the use of GM speed as a practical marker for setting endurance training intensities.
More Related Videos
Related Concept Videos
Muscle Recovery and Fatigue
Metabolic States of the Body: The Postabsorptive State
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Metabolic States of the Body: Fasting and Starvation
What is Glycolysis?
Cells make energy by breaking down macromolecules. Cellular respiration is the biochemical process that converts "food energy" (from the chemical bonds of macromolecules) into chemical energy in the form of adenosine triphosphate (ATP). The first step of this tightly regulated and intricate process is glycolysis. The word glycolysis originates from the Latin glyco (sugar) and lysis (breakdown). Glycolysis serves two main intracellular functions: generating ATP and generating...
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...

