[Recording of synaptic currents with extracellular electrodes]
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Updated: Jun 22, 2026

Extracellular Recording of Neuronal Activity Combined with Microiontophoretic Application of Neuroactive Substances in Awake Mice
Published on: May 21, 2016
Abstract:
Recordings made by multielectrodes distributed in depth of the cortex are used for the system level study of the brain. The distribution of the extracellular potential obtained contains information about the input signals of pyramidal neurons in the cortex, the synaptic currents. A method of the estimation of the synaptic current distribution is described, which is based on the solution of the reverse problem for a system of homogeneously distributed parallel cylinders as a model of dendrites of the pyramidal neurons. The estimations are compared to the data both known from literature and obtained by an independent model.
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